Interestingly, this mission order differs from our suggested ME1 Mission Order and optimum ME2 Mission Order in one key way - and that's that there are a few missions in ME3 where if you don't complete them at the right time, you can have major negative consequences for classic beloved characters. Like with its predecessors, we have thoughts on the optimum mission order for Mass Effect 3.
Due to the very nature of its storyline, Mass Effect 3 is without a doubt the most linear of the original Mass Effect trilogy - but there's still a bit of freedom in how and when you tackle its missions, which can only mean one thing.